anti-Thioredoxin Reductase 1 antibody
Product Sizes
100 ug
£616.00
ARG63486-100UG
About this Product
- SKU:
- ARG63486
- Additional Names:
- Thioredoxin reductase 1, cytoplasmic; EC 1.8.1.9; Gene associated with retinoic and IFN-induced mortality 12 protein; Gene associated with retinoic and interferon-induced mortality 12 protein; TR; TXNR; TRXR1; KM-102-derived reductase-like factor; TR1; GRIM-12; Thioredoxin reductase TR1
- Application:
- IHC-Paraffin, Western Blot
- Buffer:
- Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
- Host:
- Goat
- Immunogen:
- TKRSGASILQAGC
- Isotype:
- IgG
- Purification:
- Purified from goat serum by antigen affinity chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is expected to recognise reported isoform 1 (NP_003321.2), isoform 2 (NP_877393.1; NP_877419.1; NP_877420.1) and isoform 3 (NP_001087240.1)
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG63486.html
