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Antibodies

anti-SPHK1 antibody

Product Sizes
100 ul
£360.00
ARG56527-100UL
250 ul
£509.00
ARG56527-250UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG56527
Additional Names:
SK 1; SPK 1; EC 2.7.1.91; SPHK; Sphingosine kinase 1
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Host:
Rabbit
Immunogen:
Synthetic peptide around an internal region of Human SPHK1.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Amphibian, Human, Mouse, Porcine, Rabbit
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody