anti-SPHK1 antibody
Product Sizes
100 ul
£450.00
ARG55846-100UL
About this Product
- SKU:
- ARG55846
- Additional Names:
- SK 1; SPK 1; EC 2.7.1.91; SPHK; Sphingosine kinase 1
- Application:
- IHC-Paraffin, Western Blot
- Buffer:
- PBS and 0.09% (W/V) Sodium azide
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide corresponding to aa. 59-89 (N-terminus) of Human SPHK1.
- Isotype:
- IgG
- Purification:
- SAS Precipitated; Dialysis
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG55846.html
