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Antibodies

anti-CCL2 / MCP1 antibody

Product Sizes
100 ul
£450.00
ARG54724-100UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG54724
Additional Names:
MCP1; Monocyte chemotactic and activating factor; MCAF; Monocyte chemotactic protein 1; Monocyte secretory protein JE; HSMCR30; Small-inducible cytokine A2; HC11; SMC-CF; GDCF-2; SCYA2; C-C motif chemokine 2; Monocyte chemoattractant protein 1; MCP-1
Application:
Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS and 0.09% (W/V) Sodium azide
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
Host:
Rabbit
Immunogen:
KLH-conjugated synthetic peptide corresponding to aa. 62-89 (C-terminus) of Human CCL2 (NP_002973.1).
Isotype:
IgG
Purification:
SAS Precipitated; Dialysis
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody