anti-NIK antibody
Product Sizes
50 ug
£466.00
ARG54322-50UG
About this Product
- SKU:
- ARG54322
- Additional Names:
- NIK; HSNIK; FTDCR1B; HS; EC 2.7.11.25; HsNIK; Serine/threonine-protein kinase NIK; NF-kappa-beta-inducing kinase; Mitogen-activated protein kinase kinase kinase 14
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS (pH 7.4) and 0.02% Sodium azide
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Nuclear factor kappa B (NF-K KappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-K KappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFA Alpha, LPS, and mitogens. A serine/threonine protein kinase which mediates NF-K KappaB activation by IL-1, TNFA Alpha, and CD95 has been identified and designated NIK (for NF-K KappaB inducing kinase). NIK is an activator of IK KappaB kinase alpha and beta (IKKA Alpha and IKKB Beta). Therefore, NIK is a key molecule in the NF-K KappaB signaling pathway leading to the expression of a variety of gene products in response to pro-inflammatory cytokines and bacterial products.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to aa 931-947 of human NIK (accession no. Q99558).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG54322.html
