anti-CD6 antibody [MEM-98] (PE)
Product Sizes
100 tests
£526.00
ARG53883-100TESTS
About this Product
- SKU:
- ARG53883
- Additional Names:
- CD antigen CD6; TP120; T-cell differentiation antigen CD6; T12
- Application:
- Flow Cytometry
- Buffer:
- PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MEM-98
- Clonality:
- Monoclonal
- Conjugate:
- R-PE
- Extra Details:
- CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
- Host:
- Mouse
- Immunogen:
- Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).
- Isotype:
- IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The clone MEM-98 reacts with CD6, a 100-130 kDa single chain transmembrane glycoprotein expressed on T and B lymphocytes subsets, thymocytes, and acute lymphocytic leukemia cells.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG53883.html
