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Antibodies

anti-CD117 / c-Kit antibody

Product Sizes
500 ul
£456.00
ARG52673-500UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG52673
Additional Names:
PBT; C-Kit; Tyrosine-protein kinase Kit; CD antigen CD117; Mast/stem cell growth factor receptor Kit; CD117; Proto-oncogene c-Kit; SCFR; Piebald trait protein; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; p145 c-kit; EC 2.7.10.1
Application:
IHC-Paraffin, Immunocytochemistry, Immunofluorescence
Buffer:
PBS (pH 7.6), 1% BSA and
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
Recognizes a protein of 145kDa, which is identified as CD117/p145kit. This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit. It precipitates both the unoccupied as well as the occupied form of c-kit. The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival. C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis.
Host:
Rabbit
Immunogen:
Synthetic peptide from the cytoplasmic domain of human CD117/c-kit protein.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody