anti-CD276 / B7-H3 antibody [2A7]
Product Sizes
50 ug
£456.00
ARG46029-50UG
About this Product
- SKU:
- ARG46029
- Additional Names:
- CD276; B7-H3; B7 homolog 3; B7H3; 4Ig-B7-H3; B7RP-2; Costimulatory molecule; CD antigen CD276; CD276 antigen
- Application:
- Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- PBS and 0.02% Sodium azide.
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 2A7
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Host:
- Mouse
- Immunogen:
- Extracellular domain of human CD276 / B7-H3.
- Isotype:
- IgG1, kappa
- Purification:
- Purification with Protein A
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG46029.html
