anti-MASP1 antibody [4F19]
Product Sizes
50 ug
£584.00
ARG45341-50UG
About this Product
- SKU:
- ARG45341
- Additional Names:
- MASP1; MBL Associated Serine Protease 1; Mannose-Binding Lectin-Associated Serine Protease 1; MASP-3; Map44; MAP-1; CRARF; PRSS5; MASP; Complement-Activating Component Of Ra-Reactive Factor; Mannose-Binding Protein-Associated Serine Protease; C4/C2 Activating Component Of Ra-Reactive Factor; Mannan Binding Lectin Serine Peptidase 1; Mannan-Binding Lectin Serine Protease 1; Ra-Reactive Factor Serine Protease P100; Complement Factor MASP-3; Serine Protease 5; CRARF1; RaRF; Mannan-Binding Lectin Serine Peptidase 1 (C4/C2 Activating Component Of Ra-Reactive Factor); Mannose-Associated Serine Protease 1; MASP-1; MASP3; 3MC1; MAP1; Complement MASP3
- Application:
- IHC-Paraffin
- Buffer:
- PBS
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 4F19
- Clonality:
- Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- Host:
- Mouse
- Immunogen:
- Recombinant Human MASP1.
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG45341.html
