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Antibodies

anti-TRAF3 antibody

Product Sizes
50 ug
£456.00
ARG44756-50UG
About this Product
SKU:
ARG44756
Additional Names:
LMP1-associated protein 1; EC 6.3.2.-; CD40 receptor-associated factor 1; LAP1; CAP-1; CD40-binding protein; CAP1; CD40BP; IIAE5; CRAF1; CD40bp; TNF receptor-associated factor 3
Application:
IHC-Paraffin, Immunoprecipitation
Buffer:
PBS with 0.09% sodium azide
CE/IVD:
RUO
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]
Host:
Mouse
Immunogen:
TRAF3
Isotype:
IgG1
Purification:
Protein A Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody