anti-CD137L / TNFSF9 antibody [CD137L/1547]
Product Sizes
50 ug
£477.00
ARG43310-50UG
About this Product
- SKU:
- ARG43310
- Additional Names:
- 4-1BBL; 4-1BB ligand; Tumor necrosis factor ligand superfamily member 9; 4-1BB-L; CD137L
- Application:
- Flow Cytometry, IHC-Paraffin
- Buffer:
- PBS, 0.05% Sodium azide and 0.1 mg/ml BSA.
- CE/IVD:
- RUO
- translate.label.attr.clone:
- CD137L/1547
- Clonality:
- Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [provided by RefSeq, Oct 2008]
- Host:
- Mouse
- Immunogen:
- Recombinant full-length Human CD137L / TNFSF9 protein.
- Isotype:
- IgG2a, kappa
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG43310.html
