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Antibodies

anti-CD137 antibody [4-1BB/3201]

Product Sizes
50 ug
£477.00
ARG43309-50UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG43309
Additional Names:
ILA; CD137; T-cell antigen 4-1BB homolog; CDw137; T-cell antigen ILA; 4-1BB; CD antigen CD137; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor
Application:
Flow Cytometry, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS, 0.05% Sodium azide and 0.1 mg/ml BSA.
CE/IVD:
RUO
translate.label.attr.clone:
4-1BB/3201
Clonality:
Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
Recombinant protein fragment within aa. 19-188 of Human CD137.
Isotype:
IgG1, kappa
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Flow Cytometry: MeOH-fixed HEK293 cells stained with ARG43309 anti-CD137 antibody [4-1BB/3201] (blue) or isotype control (red).
Immunofluorescence: MeOH-fixed HEK293 cells stained with ARG43309 anti-CD137 antibody [4-1BB/3201] (green) and Reddot nuclear stain (red).
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human spleen tissue. Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT. The tissue section was stained with ARG43309 anti-CD137 antibody [4-1BB/3201].
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human cerebellum tissue. Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT. The tissue section was stained with ARG43309 anti-CD137 antibody [4-1BB/3201].
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human renal cell carcinoma. Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT. The tissue section was stained with ARG43309 anti-CD137 antibody [4-1BB/3201].