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Antibodies

anti-CD135 / FLT3 antibody

Product Sizes
50 ug
£408.00
ARG43120-50UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG43120
Additional Names:
CD135; FLK2; Receptor-type tyrosine-protein kinase FLT3; FLK-2; STK-1; STK1; FL cytokine receptor; FLT-3; Stem cell tyrosine kinase 1; Fetal liver kinase-2; Fms-like tyrosine kinase 3; CD antigen CD135; EC 2.7.10.1
Application:
IHC-Paraffin, Western Blot
Buffer:
0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose.
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to E62-E295 of Mouse CD135 / FLT3.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody
Immunohistochemistry: Paraffin-embedded Mouse small intestine tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43120 anti-CD135 / FLT3 antibody at 1 ug/ml dilution, overnight at 4°C.
Immunohistochemistry: Paraffin-embedded Rat kidney tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43120 anti-CD135 / FLT3 antibody at 1 ug/ml dilution, overnight at 4°C.
Immunohistochemistry: Paraffin-embedded Rat liver tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43120 anti-CD135 / FLT3 antibody at 1 ug/ml dilution, overnight at 4°C.
Immunohistochemistry: Paraffin-embedded Rat small intestine tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43120 anti-CD135 / FLT3 antibody at 1 ug/ml dilution, overnight at 4°C.
Immunohistochemistry: Paraffin-embedded Mouse kidney tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG43120 anti-CD135 / FLT3 antibody at 1 ug/ml dilution, overnight at 4°C.