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Antibodies

anti-CD134 / OX40 antibody [Ber-ACT35] (PE)

Product Sizes
50 tests
£408.00
ARG42336-50TESTS
Academic Pricing
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About this Product
SKU:
ARG42336
Additional Names:
CD134; TAX transcriptionally-activated glycoprotein 1 receptor; TXGP1L; OX40L receptor; Tumor necrosis factor receptor superfamily member 4; OX40; CD antigen CD134; IMD16; ACT35 antigen; ACT35
Application:
Flow Cytometry
Buffer:
PBS and 15 mM Sodium azide.
CE/IVD:
RUO
translate.label.attr.clone:
Ber-ACT35
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Host:
Mouse
Immunogen:
HTLV 1-transformed HUT-102 cells.
Isotype:
IgG1, kappa
Purification:
Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody Ber-ACT35 (also known as ACT35) recognizes an extracellular epitope of CD134 (TNFRSF4, OX40), an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cells stained with ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) at 10 ul / 10^6 cells in 100 ul of cell suspension.
Flow Cytometry: Human PHA stimulated peripheral blood mononuclear cells stained with ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) at 10 ul / 10^6 cells in 100 ul of cell suspension and ARG53800 anti-CD25 antibody [MEM-181] (APC) at 10 ul / 100 ul of peripheral whole blood.
Flow Cytometry: Separation of Human CD134 positive CD25 positive cells (red-filled) from CD134 negative CD25 negative cells (black-dashed). Human PHA stimulated peripheral blood mononuclear cells stained with ARG42336 anti-CD134 / OX40 antibody [Ber-ACT35] (PE) at 10 ul / 10^6 cells in 100 ul of cell suspension.