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Antibodies

anti-Nectin 1 antibody [R1.302] (PE)

Product Sizes
50 tests
£408.00
ARG42295-50TESTS
Academic Pricing
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About this Product
SKU:
ARG42295
Additional Names:
HveC; nectin-1; PVRR1; PVRR; HV1S; Nectin-1; PRR1; HIgR; SK-12; CD111; CD antigen CD111; Herpesvirus Ig-like receptor; CLPED1; OFC7; ED4; PRR; Herpes virus entry mediator C; Herpesvirus entry mediator C; Poliovirus receptor-related protein 1; HVEC
Application:
Flow Cytometry
Buffer:
PBS and 15 mM Sodium azide.
CE/IVD:
RUO
translate.label.attr.clone:
R1.302
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
Host:
Mouse
Immunogen:
NIH/3T3 cells transfected with Human Nectin 1.
Isotype:
IgG1, kappa
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Flow Cytometry: Separation of human CD34 positive stem cells (blue) from lymphocytes (red). Human peripheral whole blood stained with ARG42295 anti-Nectin 1 antibody [R1.302] (PE) at 1 ug/ml dilution.