anti-CD86 antibody [BU63] (low endotoxin)
Product Sizes
100 ug
£477.00
ARG42258-100UG
About this Product
- SKU:
- ARG42258
- Additional Names:
- B70; B7.2; LAB72; CD antigen CD86; B7-2; FUN-1; CD28LG2; T-lymphocyte activation antigen CD86; CTLA-4 counter-receptor B7.2; Activation B7-2 antigen; BU63
- Application:
- Cell-based/Functional Assay, Flow Cytometry, IHC-Frozen, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- CE/IVD:
- RUO
- translate.label.attr.clone:
- BU63
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
- Host:
- Mouse
- Immunogen:
- B-lymphoblastoid cell line ARH-77.
- Isotype:
- IgG1
- Purification:
- Protein A Purified; Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The mouse monoclonal antibody BU63 reacts with an extracellular epitope of CD86 (B7-2), a 70 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG42258.html
