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Antibodies

anti-CD276 / B7-H3 antibody

Product Sizes
100 ul
£477.00
ARG41826-100UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG41826
Additional Names:
B7-H3; B7 homolog 3; B7H3; 4Ig-B7-H3; B7RP-2; Costimulatory molecule; CD antigen CD276; CD276 antigen
Application:
Flow Cytometry, Immunoprecipitation, Western Blot
Buffer:
PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Host:
Rabbit
Immunogen:
Synthetic peptide of Human CD276 / B7-H3.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody