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Antibodies

Phospho IGF1 Receptor Antibody Duo (Total, pY1161)

Product Sizes
1 pair
£573.00
ARG30240-1PAIR
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG30240
Additional Names:
Phospho IGF1 Receptor antibody; Phospho Insulin-like growth factor 1 receptor antibody; Phospho IGF1R antibody; IGF1 Receptor antibody; IGF1 Receptor phospho (Tyr1161) antibody
CE/IVD:
RUO
Extra Details:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Immunogen:
IGF1 Receptor
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Antibody Duo
Western Blot: extracts from 293 cells stained with anti-IGF-1R antibody ARG51076 and the same antibody preincubated with blocking peptide.
Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-IGF-1R antibody ARG51076 (left) or the same antibody preincubated with blocking peptide (right).
Immunofluorescence: methanol-fixed MCF cells stained with anti-IGF-1R antibody ARG51076.
Western blot: 293 and SKOV3 cells treated or un-treated with insulin stained with IGF-1R antibody (Line 1, 2 and 3) and IGF-1R (phospho-Tyr1161) antibody (ARG51590, Line 4 and 5). Line3 and Line4 also pre-incubated with the peptides used for antibody raising.
Immunohistochemistry: paraffin- embedded human breast carcinoma tissue stained with anti-IGF-1R (phospho Tyr1161) antibody ARG51590).