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Antibodies

anti-CD276 / B7-H3 antibody [MJ8] (PE)

Product Sizes
50 tests
£408.00
ARG23658-50TESTS
Academic Pricing
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About this Product
SKU:
ARG23658
Additional Names:
B7-H3; B7 homolog 3; B7H3; 4Ig-B7-H3; B7RP-2; Costimulatory molecule; CD antigen CD276; CD276 antigen
Application:
Flow Cytometry
Buffer:
PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose.
CE/IVD:
RUO
translate.label.attr.clone:
MJ8
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Host:
Rat
Immunogen:
Mouse IgG2a Fc-CD276 (aa 1-242).
Isotype:
IgG2b
Purification:
Protein G Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody