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Antibodies

anti-PDE11A phospho (Ser117 / Ser124) antibody

Product Sizes
50 ug
£466.00
ARG10817-50UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG10817
Additional Names:
EC 3.1.4.35; PPNAD2; Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; cAMP and cGMP phosphodiesterase 11A; EC 3.1.4.53
Application:
ELISA, Immunoprecipitation, Western Blot
Buffer:
Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
Synthetic peptide taken within aa. 100-150 from PDE11A protein. Phosphorylated at Ser117 and Ser124.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody