Recombinant Human NPC1 Protein, N-His
Product Sizes
50 ug
£168.00
YHA41901-50UG
100 ug
£327.00
YHA41901-100UG
1 mg
£1145.00
YHA41901-1MG
About this Product
- SKU:
- YHA41901
- Additional Names:
- NPCintracellularcholesteroltransporter1,Niemann-PickC1protein,NPC1,receptorforebolavirus,receptorforebolavirus
- Application:
- ELISA, SDS-PAGE, Western Blot
- Buffer:
- LyophilizedfromasolutioninPBSpH7.4,0.02%NLS,1mMEDTA,4%Trehalose,1%Mannitol.
- Extra Details:
- NPC1/Niemann-PickC1protein(Microbialinfection)Actsasanendosomalentryreceptorforebolavirus. IntracellularcholesteroltransporterwhichactsinconcertwithNPC2andplaysanimportantroleintheegressofcholesterolfromtheendosomal/lysosomalcompartment.UnesterifiedcholesterolthathasbeenreleasedfromLDLsinthelumenofthelateendosomes/lysosomesistransferredbyNPC2tothecholesterol-bindingpocketintheN-terminaldomainofNPC1.CholesterolbindstoNPC1withthehydroxylgroupburiedinthebindingpocket.Bindsoxysterolwithhigheraffinitythancholesterol.Mayplayaroleinvesiculartraffickinginglia,aprocessthatmaybecrucialformaintainingthestructuralandfunctionalintegrityofnerveterminals(Probable).
- Molecular Weight:
- 29.31kDa
- Physical State:
- Lyophilized
- Purity:
- >90% as determined by sds-page.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- AntibodySystem
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
