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Antibodies

Anti-NeuGcGM3/GM3 Antibody (chP3)

Product Sizes
100 ug
£384.00
RGK11202-100UG
1 mg
£1304.00
RGK11202-1MG
About this Product
SKU:
RGK11202
Additional Names:
NeuGcGM3, Ganglioside N-glycolyl GM3, N-glycolylneuraminic acid -NeuGc, NGNA-GM3 ganglioside, NeuGcGM3
Application:
ELISA, Immunohistochemistry
Buffer:
0.01M PBS, pH 7.4.
translate.label.attr.clone:
chP3
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Chimeric P3 antibody specifically reacted with GM3(NeuGc) and GM2(NeuGc) gangliosides, and not with their acetylated variants.The chimeric antibody chP3 selectively recognizes a broad variety of NeuGc gangliosides, showing no cross-reactivity to the highly similar N-acetylated (NeuAc) gangliosidesWe have further investigated the interaction of chP3 with its anti-idiotypic antibody, 1E10 (also known as Racotumomab), currently in clinical trials as a cancer vaccine.
Host:
Mouse
Immunogen:
NeuGcGM3, Ganglioside N-glycolyl GM3, N-glycolylneuraminic acid -NeuGc, NGNA-GM3 ganglioside, NeuGcGM3
Isotype:
IgG2a, kappa
Physical State:
Liquid
Purity:
>95%
Purification:
Protein A/G purified from cell culture supernatant.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Supplier:
AntibodySystem
Type:
Antibody: Monoclonal Antibody