Glofitamab ELISA Kit
Product Sizes
96 tests
£1373.00
KDC90704-96TESTS
About this Product
- SKU:
- KDC90704
- Additional Names:
- CD20-TCB (2:1), RG-6026, CAS: 2229047-91-8
- Application:
- ELISA
- Extra Details:
- Glofitamab (RG6026) is a novel T-cell-engaging, bispecific antibody that binds bivalently to CD20 on B cells, and monovalently to CD3 on T cells. In study NP30179 (NCT03075696), an ongoing Phase I/II dose-escalation and expansion study, glofitamab fixed-dosing (0.6-25mg) with obinutuzumab pre-treatment (Gpt) achieved high, durable CRs with manageable safety in pts with heavily pre-treated R/R NHL (Dickinson et al. EHA 2020). Step-up dosing (SUD) of glofitamab, in addition to Gpt, allowed dose-escalation up to the highest planned dose of 30mg to maximize efficacy, while mitigating cytokine release syndrome (CRS; [Hutchings et al. J Clin Oncol 2021]). We present updated duration of response (DoR) data from the glofitamab monotherapy fixed-dosing and SUD cohorts of study NP30179 in pts with R/R NHL.
- Format:
- Colorimetric
- Immunogen:
- Glofitamab
- Physical State:
- Plasma, Serum
- Range:
- 0.31-5 ug/mL
- Sensitivity:
- 0.156 ug/ml
- Shipping Conditions:
- Blue Ice
- Supplier:
- AntibodySystem
- Type:
- Assay Kits: ELISAs
