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Assay Kits & ELISAs

Ganitumab ELISA Kit

Product Sizes
96 tests
£1111.00
KDC29904-96TESTS
About this Product
SKU:
KDC29904
Additional Names:
AMG 479, CAS: 905703-97-1
Application:
ELISA
Extra Details:
Ganitumab (AMG-479) is a mAb against IGF-IR which also inhibits binding of both IGF-1 and IGF-2 ligands to IGF-IR. The therapeutic value of AMG-479 was evaluated in several preclinical settings including androgen-dependent prostate cancer, and combined with androgen-deprivation therapy. Ganitumab was found to be most potent against VCaP xenografts when it was used in combination with complete androgen-deprivation therapy. After 4 weeks of treatment, tumor volume was reduced by 72% and growth suppression was maintained over 16 weeks of treatment. These findings suggested that the use of ganitumab in conjunction with androgen-deprivation therapy may be beneficial in the treatment of prostate cancer.
Format:
Colorimetric
Immunogen:
Ganitumab
Physical State:
Plasma, Serum
Range:
0.31-5 ug/mL
Sensitivity:
0.156 ug/ml
Shipping Conditions:
Blue Ice
Supplier:
AntibodySystem
Type:
Assay Kits: ELISAs