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Antibodies

Research Grade Motavizumab

Product Sizes
1 mg
£506.00
DVV02803-1MG
5 mg
£1169.00
DVV02803-5MG
25 mg
£2865.00
DVV02803-25MG
About this Product
SKU:
DVV02803
Additional Names:
MEDI-524,NUMAX, NISTmAb, CR9503, CAS: 677010-34-3
Buffer:
0.01M PBS, pH 7.4.
translate.label.attr.clone:
Motavizumab
Clonality:
Recombinant Monoclonal
Concentration:
2.8 mg/ml
Extra Details:
Motavizumab (MEDI-524, NUMAX, NISTmAb) is a second generation monoclonal antibody (mAb) derived from palivizumab (Synagis) using affinity maturation techniques. Motavizumab is currently undergoing US Food and Drug Administration review as a treatment for respiratory syncytial virus (RSV) prophylaxis. It has been evaluated in large-scale clinical studies, and has demonstrated efficacy in reducing the disease burden of RSV in high-risk infant populations.Motavizumab (MEDI-524, NUMAX, NISTmAb) has higher affinity and a longer half-life, was effective in reducing RSV hospitalization in high-risk full-term infants in the US, but was not licensed due to safety concerns (allergic reactions) .
Host:
Human
Immunogen:
F, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1
Isotype:
IgG1, kappa
Physical State:
Liquid
Purity:
>95%
Purification:
Protein A/G purified from cell culture supernatant.
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Source:
XtenCHO
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Supplier:
AntibodySystem
Type:
Antibody: Recombinant Antibodies