Polatuzumab vedotin-piiq (ADC)
Product Sizes
1 mg
£1180.00
DHE26399-1MG
5 mg
£4366.00
DHE26399-5MG
About this Product
- SKU:
- DHE26399
- Additional Names:
- Polivy
- translate.label.attr.clone:
- Polatuzumab vedotin-piiq
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
- Immunogen:
- CD79b
- Physical State:
- Liquid
- Purity:
- >90% as determined by sec.
- Purification:
- Ion Exchange
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- AntibodySystem
- Type:
- Antibody: Recombinant Antibodies
