Anti-H3R2me2(sym)K4me2 | Histone H3
Product Sizes
50 ug
£576.00
AS163185-50UG
About this Product
- SKU:
- AS163185
- Application:
- ChIP
- Clonality:
- Polyclonal
- Extra Details:
- Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine. The dimethylation of both arginine 2 (H3R2me2) and lysine 4 (H3K4me2) of H3 are both known marks to have opposing affects. R2me2 maintains transcriptional silence by silencing Set1 mediated K4 methylation, in which K4 methylation is normally associated with active chromatin. The protein arginine methyltransferase PRMT6 can methylate H3R2 in vivo, and overexpression of this enzyme downregulates Hox and Myc dependent genes, both of which are targets of H3K4 methylation.
- Format:
- Liquid
- Formulation:
- Immunogen affinity purified serum.
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide
- Molecular Weight:
- 15 kDa
- Physical State:
- Liquid
- Purity:
- Immunogen affinity purified serum.
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Plant, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- Supplier:
- Agrisera
- Type:
- Antibodies:Polyclonal Antibody
