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Antibodies

Anti-Transthyretin 56-61, amyloid specific

Product Sizes
100 ug
£391.00
AS163113-100UG
About this Product
SKU:
AS163113
Application:
ELISA
Clonality:
Monoclonal
Extra Details:
Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 10% of the population above 80 years of age with depositions mainly found in the heart.Monoclonal IgG1 antibody. Amyloid specific for human Transthyretin. Detects the C-terminal fragment 49-127 frequently formed in vivo.
Format:
Lyophilized
Formulation:
Affinity purified in PBS pH 7.4.
Host:
Mouse
Immunogen:
Recombinant protein corresponding to the Human wild type Transthyretin. GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE The epitope has been mapped to residue 56-61
Isotype:
IgG1
Molecular Weight:
155
Physical State:
Lyophilized
Purity:
Affinity purified in PBS pH 7.4.
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Store lyophilized/reconstituted at 4°C, Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Supplier:
Agrisera
Type:
Antibodies:Monoclonal Antibody