Anti-Amyloid beta oligomer-specific monoclonal antibody
Product Sizes
50 ug
£435.00
AS10932-50UG
About this Product
- SKU:
- AS10932
- Application:
- ELISA
- Clonality:
- Monoclonal
- Extra Details:
- Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species.
- Format:
- Lyophilized
- Formulation:
- Affinity purified in PBS pH 7.4.
- Host:
- Mouse
- Immunogen:
- Partly aggregated, recombinant peptide corresponding to the human Abeta (1-40/42). Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V. The epitope is 3-8. The molecular weight of immunogen is 4.5 kDa.
- Isotype:
- IgM
- Molecular Weight:
- 4.5 kDa
- Physical State:
- Lyophilized
- Purity:
- Affinity purified in PBS pH 7.4.
- Purification:
- Affinity Purified
- Reactivities:
- Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store lyophilized/reconstituted at 4°C. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
- Supplier:
- Agrisera
- Type:
- Antibodies:Monoclonal Antibody
