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Proteins and Peptides

Mouse VEGF R1 / Flt-1 Protein, Mouse IgG2a Fc Tag, low endotoxin

Product Sizes
100 ug
£348.00
VE1-M5256-100UG
1 mg
£2314.00
VE1-M5256-1MG
About this Product
SKU:
VE1-M5256
Additional Names:
FLT|FLT1|VEGFR1
Buffer:
50 mM Tris, 100 mM Glycine, pH7.5
Extra Details:
Vascular endothelial growth factor receptor 1 (VEGFR1) is also known as Fms-like tyrosine kinase 1 (FLT-1), Tyrosine-protein kinase receptor FLT, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR1 is detected in normal lung, but also in placenta, liver, kidney, heart and brain tissues and specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR1 acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. VEGFR1 may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. VEGFR1 can promote endothelial cell proliferation, survival and angiogenesis in adulthood.
Immunogen:
VEGF R1
Molecular Weight:
109.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Mouse VEGF R1 Protein, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
Immobilized Human VEGF165,Native (Cat. No. VE5-H4210) at 2 ug/mL (100 uL/well) can bind Mouse VEGF R1 Protein, Mouse IgG2a Fc Tag (Cat. No. VE1-M5256) with a linear range of 2-31 ng/mL (QC tested).
Immobilized Human VEGF-B, His Tag (Cat. No. VE6-H5225) at 2 ug/mL (100 uL/well) can bind Mouse VEGF R1 Protein, Mouse IgG2a Fc Tag (Cat. No. VE1-M5256) with a linear range of 8-63 ng/mL (Routinely tested).