Human UCH-L1 Protein, His Tag
Product Sizes
50 ug
£259.00
UC1-H5140-50UG
1 mg
£1,553.00
UC1-H5140-1MG
About this Product
- SKU:
- UC1-H5140
- Additional Names:
- PGP9.5|UCHL1
- Buffer:
- 50 mM Tris, 150 mM Nacl, pH8.0
- Extra Details:
- Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1) ,a member of the peptidase C12 family, is also known as neuron cytoplasmic protein 9.5 (PGP 9.5) and ubiquitin thioesterase L1.About 30% of total UCHL1 is associated with membranes in brain. UCHL1 is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also,UCHL1 can bind to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity. Furthermore, the mutations of UCHL1 gene can result in parkinson disease 5.
- Molecular Weight:
- 25.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes