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Proteins and Peptides

Human TYRO3 / Dtk Protein, Fc Tag

Product Sizes
200 ug
£318.00
TY3-H5251-200UG
1 mg
£1272.00
TY3-H5251-1MG
About this Product
SKU:
TY3-H5251
Additional Names:
BYK|DTK|RSE|SKY|TIF|TYRO3
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.
Immunogen:
TYRO3
Molecular Weight:
68.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Human TYRO3, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human GAS6 Protein, His Tag (Cat. No. GA6-H5246) at 10 ug/mL (100 uL/well) can bind Human TYRO3, Fc Tag (Cat. No. TY3-H5251) with a linear range of 2.5-20 ng/mL (QC tested).