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Proteins and Peptides

Human TOP2A / TOP2 Protein, Tag Free

Product Sizes
20 ug
£913.00
TOA-H5117-20UG
100 ug
£1637.00
TOA-H5117-100UG
500 ug
£4345.00
TOA-H5117-500UG
About this Product
SKU:
TOA-H5117
Additional Names:
alpha isozyme|DNA topoisomerase 2-alpha|DNA topoisomerase II|TOP2|TOP2A
Buffer:
50 mM Tris, 0.5 M KCl, pH8.0
Extra Details:
DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
Immunogen:
TOP2A
Molecular Weight:
13.0 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes