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Proteins and Peptides

Human Osteoprotegerin / TNFRSF11B Protein, His Tag

Product Sizes
100 ug
£212.00
TNB-H5220-100UG
1 mg
£1549.00
TNB-H5220-1MG
About this Product
SKU:
TNB-H5220
Additional Names:
OCIF|OPG|Osteoprotegerin|TNFRSF11B
Buffer:
PBS
Extra Details:
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) is also known as Osteoclastogenesis inhibitory factor (OCIF), Osteoprotegerin (OPG). TNFRSF11B is a secreted homodimer protein, which can interact with TNFSF10 and TNFSF11. TNFRSF11B acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TNFRSF11B inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Immunogen:
Osteoprotegerin
Molecular Weight:
44.4 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Osteoprotegerin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human TNFSF11, Fc Tag (Cat. No. RAL-H5265) at 10 ug/mL (100 uL/well) can bind Human Osteoprotegerin, His Tag (Cat. No. TNB-H5220) with a linear range of 5-156 ng/mL (QC tested).
Immobilized Human Osteoprotegerin, His Tag (Cat. No. TNB-H5220) at 5 ug/mL (100 uL/well) can bind Human TRAIL, Mouse IgG2a Fc Tag with a linear range of 0.5-16 ng/mL (Routinely tested).