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Biotinylated Human TL1A / TNFSF15 Protein, His,Avitag[TM]

Product Sizes
25 ug
£377.00
TLA-H52Q1-25UG
200 ug
£1466.00
TLA-H52Q1-200UG
About this Product
SKU:
TLA-H52Q1
Buffer:
PBS, 0.5 M Arginine, pH7.4
Conjugate:
Biotin
Extra Details:
TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.
Immunogen:
TL1A
Molecular Weight:
24.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human TL1A Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human DcR3, Fc Tag (Cat. No. TNB-H5255) at 5 ug/mL (100 uL/well) can bind Biotinylated Human TL1A Protein, His,Avitag (Cat. No. TLA-H52Q1) with a linear range of 0.2-6 ng/mL (QC tested).
Immobilized Biotinylated Human TL1A Protein, His,Avitag (Cat. No. TLA-H52Q1) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Human DcR3, Fc Tag (Cat. No. TNB-H5255) with a linear range of 0.1-3 ng/mL (Routinely tested).