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Biotinylated Cynomolgus/Rhesus macaque TL1A / TNFSF15 Protein, Avitag[TM],His Tag (MALS verified)

Product Sizes
25 ug
£197.00
TLA-C82E3-25UG
200 ug
£765.00
TLA-C82E3-200UG
About this Product
SKU:
TLA-C82E3
Buffer:
PBS, 0.2 M Arginine, pH7.4
Conjugate:
Biotin
Extra Details:
TL1A, also known as TNFSF15, is a member of the TNF superfamily. This type II transmembrane protein forms stable homotrimers via its TNF homology domain (THD) and is expressed in immune cells, including monocytes, macrophages, dendritic cells, and T cells, as well as non-immune cells like synovial fibroblasts and endothelial cells. By binding to Death Receptor 3 (DR3), TL1A modulates proliferation, activation, apoptosis, and cytokine/chemokine production in effector cells, contributing to both innate and adaptive immune homeostasis. Dysregulated TL1A expression is implicated in autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease, making it a promising therapeutic target for conditions like ulcerative colitis and Crohn's disease.
Immunogen:
TL1A
Molecular Weight:
23.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Cynomolgus/Rhesus macaque TL1A Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Biotinylated Cynomolgus/Rhesus macaque TL1A Protein, Avitag,His Tag (Cat. No. TLA-C82E3) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Human DR3 Protein, Fc Tag (Cat. No. DR3-H5253) with a linear range of 5-78 ng/mL (QC tested).
Immobilized Biotinylated Cynomolgus/Rhesus macaque TL1A Protein, Avitag,His Tag (Cat. No. TLA-C82E3) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Human DcR3, Fc Tag (Cat. No. TNB-H5255) with a linear range of 0.6-10 ng/mL (Routinely tested).