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Proteins and Peptides

Cynomolgus/Rhesus macaque TL1A / TNFSF15 Protein, His Tag, low endotoxin (MALS verified)

Product Sizes
100 ug
TLA-C5241-100UG
1 mg
TLA-C5241-1MG
About this Product
SKU:
TLA-C5241
Additional Names:
TL1A|TNFSF15|VEGI-251
Buffer:
PBS
Extra Details:
TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.
Immunogen:
TL1A
Molecular Weight:
22.3 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus/Rhesus macaque TL1A / TNFSF15, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Cynomolgus/Rhesus macaque TL1A / TNFSF15, His Tag (Cat. No. TLA-C5241) at 5 ug/mL (100 uL/well) can bind Human DcR3, Fc Tag (Cat. No. TNB-H5255) with a linear range of 0.2-10 ng/mL (QC tested).
Immobilized Human DcR3, Fc Tag (Cat. No. TNB-H5255) at 5 ug/mL (100 uL/well) can bind Cynomolgus/Rhesus macaque TL1A / TNFSF15, His Tag (Cat. No. TLA-C5241) with a linear range of 0.3-10 ng/mL (Routinely tested).