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Proteins and Peptides

Human Latent TGF-beta 3 / Latent TGFB3 Protein, His Tag

Product Sizes
50 ug
£354.00
TG3-H52H5-50UG
1 mg
£4369.00
TG3-H52H5-1MG
About this Product
SKU:
TG3-H52H5
Additional Names:
ARVD|TGF-beta3|TGFB3
Buffer:
PBS
Extra Details:
Transforming growth factor beta 3 ( TGFB3) is also known as TGF-B Beta3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and --beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial--mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
Immunogen:
TGF-beta 3
Molecular Weight:
46.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Latent TGF-beta 3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human Latent TGF-beta 3, His Tag (Cat. No. TG3-H52H5) at 2 ug/mL (100 uL/well) can bind Biotinylated Human TGFBR2, Fc,Avitag (Cat. No. TG2-H82F6) with a linear range of 0.2-2 ng/mL (QC tested).