Human TGF-beta RII / TGFBR2 Protein, Llama IgG2b Fc Tag, low Endotoxin (MALS verified)
Product Sizes
100 ug
£377.00
TG2-H5253-100UG
1 mg
£2461.00
TG2-H5253-1MG
About this Product
- SKU:
- TG2-H5253
- Buffer:
- PBS
- Extra Details:
- TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFB BetaR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-B Beta1 / TGFB1 and TGF-B Beta3 / TGFB3 with high affinity and TGF-B Beta2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
- Immunogen:
- TGF-beta RII
- Molecular Weight:
- 43.3 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
