Human TFPI Protein, His Tag (active enzyme)
Product Sizes
50 ug
£330.00
TFI-H5226-50UG
1 mg
£2573.00
TFI-H5226-1MG
About this Product
- SKU:
- TFI-H5226
- Additional Names:
- EPI|LACI|TFI|TFPI|TFPI1
- Buffer:
- PBS
- Extra Details:
- Tissue factor pathway inhibitor (TFPI) is also known as Extrinsic pathway inhibitor (EPI), Lipoprotein - associated coagulation inhibitor (LACI), is a plasma proteinase inhibitor synthesized by vascular endothelial cells and part of it is associated with glycosaminoglycans of these cells. TFPI is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). TFPI is a secreted protein with a N-terminal acidic region, three Kunitz (K) domains separated with by two linker regions, and a C-terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF); The second K domain inhibits factor Xa; The third K domain binds to heparin; The C-terminal basic region may have several functions. For example, it plays an important role in binding of TFPI to cell surfaces.
- Immunogen:
- TFPI
- Molecular Weight:
- 30.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
