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Proteins and Peptides

Human TACI / TNFRSF13B Protein, His Tag, low endotoxin

Product Sizes
100 ug
£318.00
TAI-H52H3-100UG
1 mg
£2385.00
TAI-H52H3-1MG
About this Product
SKU:
TAI-H52H3
Additional Names:
CD267|TACI|TNFRSF13B
Buffer:
PBS, 0.2 M Arginine, pH7.4
Extra Details:
Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.
Immunogen:
TACI
Molecular Weight:
20.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human TACI, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) at 2 ug/mL (100 uL/well) can bind Human TACI, His Tag (Cat. No. TAI-H52H3) with a linear range of 1-16 ng/mL (QC tested).
Immobilized Human TACI, His Tag (Cat. No. TAI-H52H3) at 2 ug/mL (100 uL/well) can bind Biotinylated Human APRIL, Fc,Avitag (Cat. No. APL-H82F5) with a linear range of 2-39 ng/mL (Routinely tested).