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Proteins and Peptides

Human TAP1 & TAP2 Full Length Protein, Flag,His Tag&Flag,Twin-Strep Tag (Detergent)

Product Sizes
20 ug
£1419.00
TA2-H55D3-20UG
100 ug
£3674.00
TA2-H55D3-100UG
500 ug
£8319.00
TA2-H55D3-500UG
About this Product
SKU:
TA2-H55D3
Buffer:
50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
Extra Details:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:
TAP1 & TAP2
Molecular Weight:
84.9 kDa & 81.1 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes