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Proteins and Peptides

Human Stathmin 1 / STMN1 Protein, His Tag

Product Sizes
100 ug
£207.00
ST1-H5149-100UG
1 mg
£1154.00
ST1-H5149-1MG
About this Product
SKU:
ST1-H5149
Additional Names:
C1orf215|LAP18|OP18|Stathmin|STMN1
Buffer:
PBS
Extra Details:
Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric A Alpha,B Beta-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.
Immunogen:
Stathmin 1
Molecular Weight:
18.1 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins