Human SSTR2 Full Length Protein (VLP)
Product Sizes
20 ug
£1237.00
SS2-H5216-20UG
100 ug
£1867.00
SS2-H5216-100UG
500 ug
£5046.00
SS2-H5216-500UG
About this Product
- SKU:
- SS2-H5216
- Additional Names:
- Smstr2|Somatostatin R2|somatostatin receptor 2|somatostatin receptor type 2|SomatostatinR2|SRIF-1|SS-2-R|SS2-R|SS2R|SST2|SSTR2
- Buffer:
- PBS
- Extra Details:
- Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an invaluable drug target for the pharmacological management of pituitary adenomas and neuroendocrine tumors. Somatostatin receptors (SSTR1, 2A and B, 3, 4 and 5) belong to the G protein coupled receptor family and have a wide expression pattern in both normal tissues and solid tumors. Investigating the function of each SSTR in several tumor types has provided a wealth of information about the common but also distinct signaling cascades that suppress tumor cell proliferation, survival and angiogenesis. This provided the rationale for developing multireceptor-targeted somatostatin analogs and combination therapies with signaling-targeted agents such as inhibitors of the mammalian (or mechanistic) target of rapamycin (mTOR). The ability of SSTR to internalize and the development of rabiolabeled somatostatin analogs have improved the diagnosis and treatment of neuroendocrine tumors.
- Immunogen:
- SSTR2
- Molecular Weight:
- 45.3 kDa | 56.1 kDa
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
