SARS-CoV-2 Spike Trimer Protein (T19R, T95I, Y145H, EF156-157del, R158G, A222V, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified)
Product Sizes
50 ug
£471.00
SPN-C52HU-50UG
500 ug
£3274.00
SPN-C52HU-500UG
About this Product
- SKU:
- SPN-C52HU
- Additional Names:
- S glycoprotein|S protein|Spike|Spike glycoprotein
- Buffer:
- 0.1 M Sodium citrate, pH5.5
- Extra Details:
- SARS-CoV-2 Spike Trimer, His Tag (SPN-C52Hu) is the ectodomain of SARS-CoV-2 S protein which contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations T19R, T95I, Y145H, EF156-157del, R158G, A222V, L452R, T478K, D614G, P681R, D950N were identified in the SARS-CoV-2 Delta Plus variant (Pango lineage: AY.4.2). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
- Immunogen:
- Spike protein
- Molecular Weight:
- 137.8 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
