SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Israel/EPI_ISL_18096761) (MALS verified)
Product Sizes
50 ug
£471.00
SPN-C524W-50UG
500 ug
£2985.00
SPN-C524W-500UG
About this Product
- SKU:
- SPN-C524W
- Buffer:
- 0.1 M Sodium citrate, pH5.5
- Extra Details:
- SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Israel/EPI_ISL_18096761) (SPN-C524w) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (ins16MPLF,T19I,R21T,LPP24-26Del,A27S,S50L,H69del,V70del,V127F,G142D,Y144del,F157S,R158G,N211del,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,K417N,N440K,V445H,G446S,N450D,L452W,N460K,S477N,T478K,N481K,V483del,E484K,F486P,Q498R,N501Y,Y505H,A570V,D614G,P621S,H655Y,I670V,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.86/Israel/EPI_ISL_18096761). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
- Immunogen:
- Spike protein
- Molecular Weight:
- 138 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
