SARS-CoV-2 Spike Trimer Protein, His Tag (XD/BA.1 x AY.4 recombinant) (MALS verified)
Product Sizes
50 ug
£471.00
SPN-C5226-50UG
500 ug
£3274.00
SPN-C5226-500UG
About this Product
- SKU:
- SPN-C5226
- Additional Names:
- S glycoprotein|S protein|Spike|Spike glycoprotein
- Buffer:
- 0.1 M Sodium citrate, pH5.5
- Extra Details:
- SARS-CoV-2 Spike Trimer, His Tag (XD/BA.1 x AY.4 recombinant) (SPN-C5226) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F, R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are predicted as the SARS-CoV-2 variant (Pango lineage: XD). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
- Immunogen:
- Spike protein
- Molecular Weight:
- 138.5 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
