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Proteins and Peptides

SARS-CoV-2 Spike Trimer Protein, His Tag (BA.3/Omicron) (MALS verified)

Product Sizes
50 ug
£471.00
SPN-C5225-50UG
500 ug
£3274.00
SPN-C5225-500UG
About this Product
SKU:
SPN-C5225
Additional Names:
S glycoprotein|S protein|Spike|Spike glycoprotein
Buffer:
0.1 M Sodium citrate, pH5.5
Extra Details:
SARS-CoV-2 Spike Trimer, His Tag (BA.3/Omicron) (SPN-C5225) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (A67V,H69del,V70del,T95I,G142D,V143del,Y144del,Y145del,N211del,L212I,G339D,S371F,S373P,S375F,D405N,K417N,N440K,G446S,S477N,T478K,E484A,Q493R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.3; GISAID clade: GRA; Nextstrain clade: 21M). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Immunogen:
Spike protein
Molecular Weight:
137.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SARS-CoV-2 Spike Trimer, His Tag (BA.3/Omicron) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 5 ug/mL (100 uL/well) can bind SARS-CoV-2 Spike Trimer, His Tag (BA.3/Omicron) (Cat. No. SPN-C5225) with a linear range of 0.078-2.5 ug/mL (QC tested).
Immobilized SARS-CoV-2 Spike Trimer, His Tag (BA.3/Omicron) (Cat. No. SPN-C5225) at 1 ug/mL (100 uL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 0.2-25 ng/mL (Routinely tested).