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Proteins and Peptides

SARS-CoV-2 Spike Trimer Protein, His Tag (JN.1/Omicron) (MALS verified)

Product Sizes
50 ug
£471.00
SPN-C5221-50UG
500 ug
£2985.00
SPN-C5221-500UG
About this Product
SKU:
SPN-C5221
Buffer:
0.1 M Sodium citrate, pH5.5
Extra Details:
SARS-CoV-2 Spike Trimer Protein, His Tag (JN.1/Omicron) (SPN-C5221) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (T19I,R21T,LPP24-26Del,A27S,S50L,H69del,V70del,V127F,G142D,Y144del,F157S,R158G,N211del,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,R408S,K417N,N440K,V445H,G446S,N450D,L452W,L455S,N460K,S477N,T478K,N481K,V483del,E484K,F486P,Q498R,N501Y,Y505H,E554K,A570V,D614G,P621S,H655Y,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: JN.1/Omicron). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Immunogen:
Spike protein
Molecular Weight:
137.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SARS-CoV-2 Spike Trimer Protein, His Tag (JN.1/Omicron) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 5 ug/mL (100 uL/well) can bind SARS-CoV-2 Spike Trimer Protein, His Tag (JN.1/Omicron) (Cat. No. SPN-C5221) with a linear range of 0.6-20 ng/mL (QC tested).
Immobilized SARS-CoV-2 Spike Trimer Protein, His Tag (JN.1/Omicron) (Cat. No. SPN-C5221) at 5 ug/mL (100 uL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 0.2-1 ng/mL (Routinely tested).