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Biotinylated Mouse SOST / Sclerostin Protein, Avitag[TM],His Tag (HPLC verified)

Product Sizes
25 ug
£430.00
SOT-M82E3-25UG
200 ug
£1943.00
SOT-M82E3-200UG
About this Product
SKU:
SOT-M82E3
Buffer:
PBS, 0.2 M Arginine, pH7.4
Conjugate:
Biotin
Extra Details:
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]
Immunogen:
SOST
Molecular Weight:
24.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Mouse SOST Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Biotinylated Mouse SOST Protein, Avitag,His Tag (Cat. No. SOT-M82E3) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Human LRP-6 (20-630), Mouse IgG2a Fc Tag (Cat. No. LR6-H5253) with a linear range of 0.3-20 ng/mL (QC tested).
Immobilized Human LRP-6 (20-630), Mouse IgG2a Fc Tag (Cat. No. LR6-H5253) at 5 ug/mL (100 uL/well) can bind Biotinylated Mouse SOST Protein, Avitag,His Tag (Cat. No. SOT-M82E3) with a linear range of 0.2-10 ng/mL (Routinely tested).